The 12th edition of the SifrARN (Structure, Integration, Function and Reactivity of RNA) conference will be held from the 3th to the 5th of October 2022 in Bordeaux, France. This conference aims at gathering people from all fields of RNA biology, to exchange and discuss unifying themes related to the importance of RNA.
RNAs play key roles in the regulation of gene expression in all living organisms and are also used as markers and therapeutic targets in many diseases including cancer and infectious diseases. The wide variety of roles and mechanisms of action of RNAs are based on their structures, modifications and interactions with proteins. The SifrARN conference will cover all aspects of RNA biology with a focus on recent technological advances to identify, detect and study RNA molecules, in order to better understand their wide range of actions.
Two keynote speakers, Prof. Dr. Joerg Vogel (The FEBS National Lecturer) and Dr. Ana Eulalio, have been invited.
Prof. Vogel is one of the founder of the Helmholtz institute for RNA-based infection research (HIRI), a structure specifically interested in understanding how and why bacteria use RNA as the main regulator during infection. To achieve those goals, the laboratory of Prof. Vogel has developed new RNA deep sequencing-based approaches to help measure RNA diversity. Their new milestones is to be able to reaching single cell sensitivity. They target bacteria linked to human biology and in particular the bacteria present in the human microbiote.
Dr. Ana Eulalio is a group leader at the Centre for Innovative Biomedicine and Biotechnology (CIBB) at the University of Coimbra, Portugal. The main focus of her research group is to understand how the non-coding genome (microRNAs and lncRNAs) and other RNA related pathways influence the interaction between host cells and bacterial pathogens during infection. To achieve this, her group applies unbiased, genome-wide systems biology approaches, including deep-sequencing and high-throughput functional screens, followed by in-depth characterization of interesting microRNAs and their targets.